Start your free 3-day trial — no credit card required, full access included

Evidence - Hemorrhoidectomy according to Milligan-Morgan

  1. Summary of the Literature

    The treatment of early hemorrhoidal disease can be conservative through dietary changes, stool regulation, sclerotherapy, and the use of rubber band ligation. If conservative measures are unsuccessful and third- or fourth-degree hemorrhoidal disease with subjectively impairing symptoms occurs, surgical therapy is required. Annually, about 50,000 people in Germany undergo surgery for hemorrhoidal disease, which accounts for only 5% of all patients treated for hemorrhoids. The disadvantages of common surgical methods include a work incapacity of 2 to 4 weeks and intense postoperative pain.

    If a resective procedure (mono- or multisegmental) is indicated, the following options are generally available:

    • open hemorrhoidectomy according to Milligan-Morgan (MM),
    • closed hemorrhoidectomy according to Ferguson (FG),
    • subanodermal/submucosal hemorrhoidectomy according to Parks (PA),
    • reconstructive hemorrhoidectomy according to Fansler-Arnold (FA).

    E. T. C. Milligan and C. N. Morgan from the United Kingdom first performed the open segment excision named after them around 1935 and reported on it in 1937 [1]. The MM procedure is the most frequently performed procedure in the surgical treatment of hemorrhoidal disease, also in Germany [2 - 5].

    Most surgeries are performed under general or regional anesthesia. Some authors also mention performing it under local anesthesia, sometimes with sedation [6, 7, 8]. The procedure is usually performed on an inpatient basis with an average stay of 3 days [9, 10]. With appropriate patient selection, the procedure can also be performed on an outpatient basis [6, 7]. The operation time varies from 10 to 40 minutes, with an average of 30 minutes [9, 10]. The duration of work incapacity varies from 7 to 30 days, with a median of 18.6 days [11].

    Postoperative pain is understandably of great importance to the patient. It seems that the extent of the procedure (1, 2, or 3 pedicles) has no impact on the duration and intensity of the pain [12].

    The frequency of postoperative partial incontinence ranges from 0 to 28% according to studies, although predominantly transient [13, 14]. Johannson determined an operation-related incontinence rate of 9.5% [15]. Another study found no differences between incontinence before and after an MM hemorrhoidectomy [16]. However, there is a possibility that a pre-existing continence disorder may intensify after an MM operation.

    Where specified, the success rates of the operation vary depending on the follow-up between 67% and 100% [9, 13, 15, 17, 18, 19]. Recurrences are reported between 0% and 7.6%, with one study indicating 12% [8, 9, 17 - 22]. In less than 2% of recorded cases, a repeat operation due to hemorrhoids was necessary.

    The rates of postoperative complications vary between 0 and 25% and mostly involve urinary retention and bleeding [18, 23]. In a small group of 25 patients, 5 patients (20%) experienced bleeding, of which only one (4%) required surgical therapy [24]. In studies with a larger number of patients, the number of bleedings is usually 1 to 2%. Postoperative stenoses or strictures occur with a frequency of up to 6%, while in a single weak RCT, it was reported at 20% [8, 20]. Stool incontinence due to sphincter injury as a long-term complication is rare at 4.5% [25].

    The use of radiofrequency (bipolar sealing instruments) leads to a shorter operation time, less bleeding, fewer anoderm resections, and less postoperative pain due to reduced thermal spread [26]. However, the effect of reduced pain is only noticeable between the 7th and 14th postoperative day and does not occur thereafter [27].

    The effectiveness of stapled hemorrhoidopexy as a non-resective and thus pexing procedure has been investigated in numerous studies. Watson et al. showed in 2016 that pain after hemorrhoidopexy is less in the short-term postoperative course (6 weeks) than after hemorrhoidectomy [28]. However, hemorrhoidectomy was favored in terms of recurrence rates, complaints, reoperations, and quality of life. The authors of a recent meta-analysis come to similar conclusions [29]. In a 2015 review study that examined the treatment of 7827 patients with third- or fourth-degree hemorrhoids, it was found that stapled hemorrhoidopexy causes more recurrences than conventional hemorrhoidectomy [30]. Other meta-analyses also show that the stapler procedure has a higher recurrence rate [31]. According to the German guideline "Hemorrhoidal Disease," stapled hemorrhoidopexy can be offered as a possible procedure for third-degree hemorrhoidal disease. Due to the increased recurrence rate compared to conventional operations, the stapler technique should not be used for fourth-degree hemorrhoidal disease [25].

    In some studies, "the MM" was combined with other procedures such as anal dilation or sphincterotomy. Although Mortensen found no significant differences in postoperative manometry between patients with or without anal dilation, three patients from the dilation group had mild incontinence after one year [32]. Galizia reports that the combination of MM with sphincterotomy reduced resting and squeezing pressures, and Mathai ended his study because the additional sphincterotomy led to high incontinence rates [8, 18]. Due to increased incontinence rates, segment excision according to Milligan-Morgan should therefore not be combined with sphincterotomy.

  2. Currently ongoing studies on this topic

  3. Literature on this topic

    1. Milligan E, Naunton Morgan C, Jones L, Officer, R: SURGICAL ANATOMY OF THE ANAL CANAL, AND THE OPERATIVE TREATMENT OF HÆMORRHOIDS. The Lancet 1937; 230(5959): 1119–24.

    2. Beattie GC, Wilson RG, Loudon MA: The contemporary management of haemorrhoids. Colorectal Dis 2002; 4(6): 450–4.

    3. Dziki L, Mik M, Trzcinski R, et al.: Surgical treatment of haemorrhoidal disease - the current situation in Poland. Prz Gastroenterol 2016; 11(2): 111–4.

    4. Herold A, Kirsch JJ: Complications after stapler hemorrhoidectomy - results of a survey in Germany. coloproctology 2001; 23(1): 8–16.

    5. Kraemer M, Bussen D, Leppert R, Sailer, M, Fuchs, KH, Thiede, A: Country-wide survey of therapeutic procedures in hemorrhoids and anal fissure. Chirurg 1998; 69(2): 215–8.

    6. Argov S: Ambulatory radical hemorrhoidectomy: personal experience with 1,530 Milligan-Morgan operations with follow-up of 2-15 years. Dig Surg 1999; 16(5): 375–8.

    7. Labas P, Ohradka B, Cambal M, Olejnik, J, Fillo, J: Haemorrhoidectomy in outpatient practice. Eur J Surg 2002; 168(11): 619–20.

    8. Galizia G, Lieto E, Castellano P, Pelosio, L, Imperatore, V, Pigantelli, C: Lateral internal sphincterotomy together with haemorrhoidectomy for treatment of haemorrhoids: a randomised prospective study. Eur J Surg 2000; 166(3): 223–8.

    9. Seow-Choen F, Ho YH, Ang HG, Goh, HS: Prospective, randomized trial comparing pain and clinical function after conventional scissors excision/ligation vs. diathermy excision without ligation for symptomatic prolapsed hemorrhoids. Dis Colon Rectum 1992; 35(12): 1165–9.

    10. Gawenda M, Walter M: Surgical therapy of advanced hemorrhoidal disease--is an ambulatory surgery intervention possible? Chirurg 1996; 67(9): 940–3.

    11. Sayfan J, Becker A, Koltun L: Sutureless closed hemorrhoidectomy: a new technique. Ann Surg 2001; 234(1): 21–4.

    12. Medina-Gallardo A, Curbelo-Pena Y, Castro X de, Roura-Poch, P, Roca-Closa, J, Caralt-Mestres, E de: Is the severe pain after Milligan-Morgan hemorrhoidectomy still currently remaining a major postoperative problem despite being one of the oldest surgical techniques described? A case series of 117 consecutive patients. Int J Surg Case Rep 2017; 30: 73–5.

    13. Argov S, Levandovsky O, Yarhi D: Milligan-Morgan hemorrhoidectomy under local anesthesia - an old operation that stood the test of time. A single-team experience with 2,280 operations. Int J Colorectal Dis 2012; 27(7): 981–5.

    14. Azizi R, Rabani-Karizi B, Taghipour MA: Comparison between Ultroid and rubber band ligation in treatment of internal hemorrhoids. Acta Med Iran 2010; 48(6): 389–93.

    15. Johannsson HO, Graf W, Pahlman L: Long-term results of haemorrhoidectomy. Eur J Surg 2002; 168(8-9): 485–9.

    16. Li Y, Xu J, Lin J, Zhu, W: Excisional hemorrhoidal surgery and its effect on anal continence. World J Gastroenterol 2012; 18(30): 4059–63.

    17. Denis J, Dubois N, Ganansia R, Du Puy-Montbrun, T, Lemarchand, N: Hemorrhoidectomy: Hospital Leopold Bellan procedure. Int Surg 1989; 74(3): 152–3.

    18. Marsh GD, Huddy SP, Rutter KP: Bupivacaine infiltration after haemorrhoidectomy. J R Coll Surg Edinb 1993; 38(1): 41–2.

    19. Bessa SS: Diathermy excisional hemorrhoidectomy: a prospective randomized study comparing pedicle ligation and pedicle coagulation. Dis Colon Rectum 2011; 54(11): 1405–11.

    20. Jones CB: A comparative study of the methods of treatment for haemorrhoids. Proc R Soc Med 1974; 67(1): 51–3.

    21. Eu KW, Seow-Choen F, Goh HS: Comparison of emergency and elective haemorrhoidectomy. Br J Surg 1994; 81(2): 308–10.

    22. Hansen JB, Jorgensen SJ: Radical emergency operation for prolapsed and strangulated haemorrhoids. Acta Chir Scand 1975; 141(8): 810–2.

    23. Ceulemans R, Creve U, van Hee R, Martens, C, Wuyts, FL: Benefit of emergency haemorrhoidectomy: a comparison with results after elective operations. Eur J Surg 2000; 166(10): 808-12; discussion 813.

    24. Tan JJ, Seow-Choen F: Prospective, randomized trial comparing diathermy and Harmonic Scalpel hemorrhoidectomy. Dis Colon Rectum 2001; 44(5): 677–9.

    25. Joos AK, Jongen J (2021) S3-Leitlinie Hämorrhoidalleiden. coloproctology 43:381–404.

    26. Milito G, Cadeddu F, Muzi MG, Nigro C, Farinon AM (2010) Haemorrhoidectomy with Ligasure vs conventional excisional techniques: meta-analysis of randomized controlled trials. Colorectal Dis 12(2):85–93

    27. Nienhuijs S, de Hingh I (2009) Conventional versus LigaSure hemorrhoidectomy for patients with symptomatic hemorrhoids. Cochrane Database Syst Rev.

    28. Watson AJ, Hudson J, Wood J et al (2016) Comparison of stapled haemorrhoidopexy with traditional excisional surgery for haemorrhoidal disease (eTHoS): a pragmatic, multicentre, randomised controlled trial. Lancet 388:2375–2385.

    29. Ruan QZ, English W, Hotouras A, Bryant C, Taylor F, Andreani S, Wexner SD, Banerjee S (2021) A systematic review of the literature assessing the outcomes of stapled haemorrhoidopexy versus open haemorrhoidectomy. Tech Coloproctol 25:19–33.

    30. Simillis C, Thoukididou SN, Slesser AAP, Rasheed S, Tan E, Tekkis PP (2015) Systematic review and network meta-analysis comparing clinical outcomes and effectiveness of surgical treatments of haemorrhoids. Br J Surg 102(13):1603–1618.

    31. Lumb KJ, Colquhoun PH, Malthaner RA, Jayaraman S (2006) Stapled versus conventional surgery for hemorrhoids. Cochrane Database Syst Rev.

    32. Mortensen PE, Olsen J, Pedersen IK, Christiansen, J: A randomized study on hemorrhoidectomy combined with anal dilatation. Dis Colon Rectum 1987; 30(10): 755–7.

  4. Reviews

    Albazee E, Alenezi A, Alenezi M, Alabdulhadi R, Alhubail RJ, Ahmad Al Sadder K, AlDabbous F, Almutairi AN, Almutairi SN, Almutairi AN, Alenezi MS. Efficacy of Harmonic Scalpel Versus Bipolar Diathermy in Hemorrhoidectomy: A Systematic Review and Meta-Analysis of Nine Randomized Controlled Trials. Cureus. 2023 Feb 7;15(2):e34734.

    Yang Y, Feng K, Lei Y, Qiu L, Liu C, Li G. Comparing the efficacy and safety of different analgesic strategies after open hemorrhoidectomy: a systematic review and network meta-analysis. Int J Colorectal Dis. 2023 Jan 7;38(1):4.

    Wee IJY, Koo CH, Seow-En I, Ng YYR, Lin W, Tan EJK. Laser hemorrhoidoplasty versus conventional hemorrhoidectomy for grade II/III hemorrhoids: a systematic review and meta-analysis. Ann Coloproctol. 2023 Feb;39(1):3-10.

    Tan VZZ, Peck EW, Sivarajah SS, Tan WJ, Ho LML, Ng JL, Chong C, Aw D, Mainza F, Foo FJ, Koh FH. Systematic review and meta-analysis of postoperative pain and symptoms control following laser haemorrhoidoplasty versus Milligan-Morgan haemorrhoidectomy for symptomatic haemorrhoids: a new standard. Int J Colorectal Dis. 2022 Aug;37(8):1759-1771

    Jin JZ, Bhat S, Lee KT, Xia W, Hill AG. Interventional treatments for prolapsing haemorrhoids: network meta-analysis. BJS Open. 2021 Sep 6;5(5). pii: zrab091.

    Aibuedefe B, Kling SM, Philp MM, Ross HM, Poggio JL. An update on surgical treatment of hemorrhoidal disease: a systematic review and meta-analysis. Int J Colorectal Dis. 2021 Sep;36(9):2041-2049.

    Dekker L, Han-Geurts IJM, Rørvik HD, van Dieren S, Bemelman WA. Rubber band ligation versus haemorrhoidectomy for the treatment of grade II-III haemorrhoids: a systematic review and meta-analysis of randomised controlled trials. Tech Coloproctol. 2021 Jun;25(6):663-674

    Ruan QZ, English W, Hotouras A, Bryant C, Taylor F, Andreani S, Wexner SD, Banerjee S. A systematic review of the literature assessing the outcomes of stapled haemorrhoidopexy versus open haemorrhoidectomy. Tech Coloproctol. 2021 Jan;25(1):19-33.

    Du T, Quan S, Dong T, Meng Q. Comparison of surgical procedures implemented in recent years for patients with grade III and IV hemorrhoids: a network meta-analysis. Int J Colorectal Dis. 2019 Jun;34(6):1001-1012.

  5. literature search

    Literature search on the pages of pubmed.