Esophagojejunostomy suture line failure 3%–10%
- Confirmation by endoscopy; sensitivity of radiological detection with water-soluble contrast agent is only 50%!
- Nothing by mouth; placement of a nasoenteric tube, broad antibiotic and possibly antifungal regimen.
- With early intervention and favorable tissue conditions, direct suture closure may still possible in rare cases.
- Fully covered self-expanding metal/plastic stent with adequate drainage of leakage cavity for defects up to 60% of circumference. Benefit: With good defect coverage the patient can eat.
- For larger defects: Endoscopic vacuum therapy (EsoSponge®)
- In large, otherwise not controllable defects with mediastinitis -> discontinuity resection with cervical diversion
Suture line failure of duodenal remnant <3%
Treatment: Adequate drainage; revision surgery usually indicated (oversew; duodenojejunostomy, partial pancreaticoduodenectomy).
Jejunojejunostomy suture line failure rare (<1%)
Treatment: Usually revision surgery.
Intraluminal secondary bleeding
- Primarily endoscopic coagulation, if unsuccessful, revision surgery indicated.
Extraluminal secondary bleeding
- Surgical revision, depending on bleeding intensity
- Bleeding source spleen: Local hemostasis sparing the spleen, if possible; splenectomy as last resort
- Note: Infection-induced erosive bleeding in duodenal stump suture line failure!
Intra-abdominal hematoma/abscess
- Ultrasound/CT-guided paracentesis and drainage
- Often concomitant with suture line failure
Lymphatic fistulas
- Possible following systematic (D2-) or extended (D3-) lymphadenectomy, rarely also chylous ascites.
- After removal of inserted drains, lymphatic fistulas usually cease spontaneously.
- Rare cases may require temporary parenteral nutrition.
Pancreatitis
- Most often edematous pancreatitis with good prognosis; nothing by mouth; nonsurgical treatment with medication.
- Hemorrhagic necrotizing pancreatitis, often resulting from iatrogenic pancreatic injury; interdisciplinary ICU treatment; also, surgical necrosectomy/lavage; Caution: High mortality!
Esophagojejunostomy transit disorders
- Origins: Edematous anastomosis, hematoma
- Remission expected within 10–14 days
- Revision surgery indicated only in exceptional cases
Secondary healing
- Treatment: Reopening wound; wound debridement, secondary wound healing; negative pressure wound therapy