Early Insufficiency of the Gastroenterostomy
- usually on the 3rd – 4th postoperative day
- Detection by endoscopy; radiological detection using water-soluble contrast medium has only a sensitivity of 50%
- Revision requirement: with early intervention and favorable tissue conditions, direct closure by oversewing may still be possible, otherwise re-establishment of the anastomosis is necessary.
Early Insufficiency of the Duodenal Stump
- surgical revision with oversewing
- if oversewing is technically not possible: external drainage of the duodenal stump via a strong Foley catheter
Late Insufficiency of the Duodenal Stump
- with good external drainage (e.g., CT-guided insertion) conservative management is possible; the resulting duodenal fistula can be anastomosed secondarily with an excluded jejunal loop
Insufficiency of the Jejunojejunostomy
- generally requires revision
Intragastric Rebleeding
- primary endoscopic hemostasis, if unsuccessful indication for surgical revision
- Reopening of the stomach by transverse incision about 4-5 cm proximal to the anastomosis and targeted suturing of the bleeding source; reclosure also in a transverse direction.
Extraluminal Rebleeding
- depending on the intensity of bleeding, surgical revision
- primarily due to lymphadenectomy or insufficient ligation of larger vessels
- Bleeding source spleen: local hemostasis with spleen preservation if possible; if splenectomy is required, gastrectomy must be performed.
Intra-abdominal Hematomas/Abscesses
- ultrasound or CT-guided puncture and drainage
- often associated with a suture insufficiency
Pancreatitis
- usually edematous pancreatitis with a good prognosis; fasting, conservative-medical treatment
- hemorrhagic-necrotizing pancreatitis often due to intraoperative pancreatic injury; intensive care-interdisciplinary treatment, also surgical necrosectomy/lavage; high mortality!
Passage Disorders of the Gastrojejunostomy
- Causes: anastomotic edema, hematoma, or residual gastric atony
- Remission expected within 10-14 days
- surgical revision very rarely indicated
Wound Healing Disorders
- Treatment: wound opening, wound toilet, secondary wound healing, abdominal wall sealing
Incomplete Resections (R1 or 2) If possible, re-exploration with the aim of complete re-resection.
Recurrence After resection of High-risk GIST either a locoregional recurrence or distant metastases (primarily intrahepatic) develop within the first 24 months.
Secondary Resistance The number of patients developing secondary resistance under ongoing TKI therapy is increasing.