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Evidence - Angle-stable palmar plate osteosynthesis of a distal radius fracture on the right

  1. Summary of the literature

    Distal radius fractures are among the most common fractures in adults, with an incidence of 20 per 10,000 people per year [1, 2]. Women are more likely to suffer a distal radius fracture than men [3]. Most distal radius fractures can be treated conservatively with immobilization, while displaced fractures often require surgery [4].

    The treatment of fractures with open reduction and internal fixation (ORIF) has significantly increased over the past decade [3]. Percutaneous pinning, external fixation, spanning plate osteosynthesis, and intramedullary nailing are additional options for stabilizing distal radius fractures [5, 6]. The method of fracture treatment varies depending on the patient (age, activity, or additional conditions) [7], local standards [8], and fracture patterns [9].

    Classifications

    Distal radius fractures are divided into different categories. The AO classification is commonly used to describe distal radius fractures and is based, like the Frykman classification, on fracture assessment in conventional X-rays [10]. The "four corner concept" with the radial, palmar, dorsal, and ulnar "corners" or fragments is described by axial computed tomography (CT) images [11]. As described by Bain et al. [12], the "corners" on the radius correlate with the attachments of the radiocarpal and radioulnar ligaments. According to Brink et al., there are eight common fracture patterns of the distal radius [11]. In the sagittal CT reconstruction, the lunate bone is often subluxated with either the dorsal or palmar fragment. This fragment, which subluxates the lunate bone, is referred to as the key fragment and should be addressed at the beginning of osteosynthesis [11]. In their classification, Hintringer et al. describe a fracture pattern-specific fragment and derive the surgical strategy from it [13].

    Principle and Goal of Surgery

    Conservative treatment can be performed for stable, non-displaced fractures. This usually involves immobilization in a forearm cast for 4 to 6 weeks [1]. Surgery is required when displaced fractures cannot be reduced closed or are unstable and re-dislocation is expected (Table 1). Functional follow-up treatment of a non-displaced fracture may be considered in exceptional cases, such as bilateral upper extremity injury. Despite good fracture alignment and lack of instability criteria, plate osteosynthesis may be recommended in this case after consultation with the patient.

    Table 1 Instability Criteria of Distal Radius Fractures
    dorsal comminution zone [14, 15]
    age > 60 years [15]
    female gender [15]
    dorsal tilt > 20° [14]
    associated distal ulna fracture (excluding avulsion of the tip of the ulnar styloid process) [15]
    radial shortening > 5 mm [14, 16]
    palmar tilt [17]

    The goal of surgical treatment is to achieve bony healing with correctly restored axis, rotation, radial/ulnar length ratio, and radial inclination, as well as anatomical reconstruction of the joint surface in intra-articular fractures. The fixation of the fragments should allow for functional postoperative treatment. If fixation principles such as Kirschner wire osteosynthesis are not functionally stable, additional immobilization with a cast is required, making functional follow-up treatment impossible.

    Plate osteosynthesis requires open fracture reduction. The majority of distal radius fractures are treated with palmar angle-stable plate osteosynthesis. The palmar approach, however, does not allow visual control of the joint surface and requires ligamentotaxis of the dorsal radiocarpal ligaments for the reduction of dorsal fragments. A dorsal approach should be performed when centrally impressed joint fragments or dorsal fragments cannot be reduced by ligamentotaxis. The dorsal approach also allows for the treatment of ligamentous or bony concomitant injuries of the proximal carpal bones. According to the literature, the dorsal approach has no negative impact on functional or radiological outcomes [18].

    In cases of central impression of the joint surface, arthroscopically assisted reduction and fixation of the fragments can also be performed. Certain fractures, such as fractures of the radial styloid process, can be treated percutaneously or arthroscopically assisted with lag screws.

    Absolute Indications for surgery include:

    • open fractures
    • fracture-dislocations
    • concomitant vascular and/or nerve injuries.

    The relative indication for surgical treatment of distal radius fractures strongly depends on the patient's needs. The indication is more liberally made in younger, active patients than in older patients with fewer functional demands. Fractures with fewer than 3 instability criteria (Table 1), where good fracture alignment has been achieved through closed reduction, can be primarily treated conservatively. To timely recognize secondary dislocation, radiological follow-up is required after about 1 and 2 weeks. Fractures that exhibit dislocation according to Table 2 and either cannot be adequately reduced or have more than three instability criteria should normally be treated surgically.

    Table 2 Limits of Acceptable Fracture Dislocation in Distal Radius Fractures
    palmar tilt
    radial shortening with ulna plus > 2 mm
    intra-articular step ≥ 1 mm
    intra-articular gap ≥ 2 mm
    dorsal tilt > 10°
    radial inclination < 15°
    coronal shift
    pathological carpal alignment

    Two additional, often less considered radiological criteria indicating operable instability are carpal alignment and coronal shift [19, 20, 21]. In a lateral X-ray, carpal alignment is assessed based on the radial axis in relation to the position of the capitate bone [22]. There are two methods to determine carpal alignment. In the first method, a line is drawn along the longitudinal axis of the radius and the capitate bone. Proper alignment is present if these two lines intersect within the carpus. In the second method, a line is drawn along the inner border of the palmar cortex of the radius. If this line intersects the center of the capitate bone, proper alignment is also present [20, 22]. A d.-p. X-ray is used to assess the coronal shift. In this case, an ulnar radial boundary line is drawn and extended distally. This line should cross the lunate bone in the middle 2/4 (26–75% of the width of the lunate lies ulnar to the intersection in healthy individuals) [21].

    Indications for the Palmar Approach

    • fractures tilted palmar
    • fractures tilted dorsal that can be reduced by ligamentotaxis

    Indications for the Dorsal Approach

    • fractures with intact palmar lip
    • a central impression ("Die-Punch Fragment")
    • need for visual control of the radiocarpal joint
    • concomitant ligament injuries (such as the scapholunate ligament)
    • fractures of the proximal carpal bones.

    Outcomes

    Even when acceptable fracture alignment could be achieved through closed reduction, prospective randomized studies have shown better functional outcomes after palmar plate osteosynthesis compared to conservative therapy for both displaced intra- and extra-articular distal radius fractures [23, 24]. Patients aged 18 to 75 years were included in these studies. It is controversial whether plate osteosynthesis and anatomical restoration are actually beneficial in older patients aged 65 years and older [25]. Older patients who have undergone either surgical or conservative therapy appear to have the same long-term outcomes (over 12 months) [26, 27, 28]. However, surgical therapy facilitates recovery and leads to better functional outcomes in the first months [27, 28]. Therefore, it is important to consider the patient's age and health status when determining the indication for surgery.

    Plate osteosynthesis is a safe operation with a postoperative complication rate of 9–15% [29, 30]. The most common complications are tendon irritations or ruptures. A meta-analysis has shown that there is no difference in complication rates between surgical and conservative therapy of distal radius fractures [25]. No difference was found between palmar and dorsal plate osteosynthesis of AO type C3 fractures in terms of complications and functional outcomes [18]. Therefore, the chosen surgical approach should be aligned with the fracture pattern to achieve anatomical reconstruction.

  2. Currently ongoing studies on this topic

  3. Literature on this topic

    1. Bentohami A, Bosma J, Akkersdijk GJM et al (2014) Incidence and characteristics of distal radial fractures in an urban population in The Netherlands. Eur J Trauma Emerg Surg 40:357–361.

    2. Bergh C, Wennergren D, Moller M, Brisby H (2020) Fracture incidence in adults in relation to age and gender: a study of 27,169 fractures in the Swedish fracture register in a well-defined catchment area. PLoS ONE 15:e244291.

    3. Azad A, Kang H, Alluri R et al (2019) Epidemiological and treatment trends of distal radius fractures across multiple age groups. J Wrist Surg 08:305–311.

    4. Rundgren J, Bojan A, Navarro CM, Enocson A (2020) Epidemiology, classification, treatment and mortality of distal radius fractures in adults: an observational study of 23,394 fractures from the national Swedish fracture register. BMC Musculoskelet Disord 21:88.

    5. Beeres FJP, Liechti R, Link B-C, Babst R (2021) Role of a spanning plate as an internal fixator in complex distal radius fractures. Operat Orthop Traumatol 33:77–88.

    6. Gradl G, Mielsch N, Wendt M et al (2014) Intramedullary nail versus volar plate fixation of extra-articular distal radius fractures. Two year results of a prospective randomized trial. Injury 45:S3–S8.

    7. Fanuele J, Koval KJ, Lurie J et al (2009) Distal radial fracture treatment. J Bone Joint Surg 91:1313–1319.

    8. Walenkamp MMJ, Mulders MAM, Goslings JC et al (2016) Analysis of variation in the surgical treatment of patients with distal radial fractures in the Netherlands. J Hand Surg Eur Vol 42:39–44.

    9. Langerhuizen D, Janssen S, Kortlever J et al (2021) Factors associated with a recommendation for operative treatment for fracture of the distal radius. J Wrist Surg 10:316–321.

    10. Graff S, Jupiter J (1994) Fracture of the distal radius: classification of treatment and indications for external fixation. Injury 25:SD14–SD25.

    11. Brink P, Rikli D (2016) Four-corner concept: CT-based assessment of fracture patterns in distal radius. J Wrist Surg 05:147–151.

    12. Bain G, Alexander J, Eng K et al (2013) Ligament origins are preserved in distal radial intraarticular two-part fractures: a computed tomography-based study. J Wrist Surg 02:255–262.

    13. Hintringer W, Rosenauer R, Pezzei Ch et al (2020) Biomechanical considerations on a CT-based treatment-oriented classification in radius fractures. Arch Orthop Trauma Surg 140:595–609.

    14. Lafontaine M, Hardy D, Delince Ph (1989) Stability assessment of distal radius fractures. Injury 20:208–210.

    15. Walenkamp MMJ, Aydin S, Mulders MAM et al (2015) Predictors of unstable distal radius fractures: a systematic review and meta-analysis. J Hand Surg Eur Vol 41:501–515.

    16. Altissimi M, Mancini GB, Azzara A, Ciaffoloni E (1994) Early and late displacement of fractures of the distal radius. Int Orthop 18:61–65

    17. Leone J, Bhandari M, Adili A et al (2004) Predictors of early and late instability following conservative treatment of extra-articular distal radius fractures. Arch Orthop Trauma Surg 124:38–41.

    18. Sangasoongsong P, Rohner-Spengler M, Delagrammaticas DE et al (2020) Comparison of fracture healing and long-term patient-reported functional outcome between dorsal and volar plating for AO C3-type distal radius fractures. Eur J Trauma Emerg Surg 46:591–598.

    19. Dy CJ, Jang E, Taylor SA et al (2014) The impact of coronal alignment on distal radioulnar joint stability following distal radius fracture. J Hand Surg 39:1264–1272.

    20. McQueen MM, Hajducka C, Court-Brown CM (1996) Redisplaced unstable fractures of the distal radius: a prospective randomised comparison of four methods of treatment. J Bone Joint Surg Br 78:404–409

    21. Trehan SK, Orbay JL, Wolfe SW (2015) Coronal shift of distal radius fractures: influence of the distal Interosseous membrane on distal radioulnar joint instability. J Hand Surg 40:159–162.

    22. Selles C, Ras L, Walenkamp M et al (2018) Carpal alignment: a new method for assessment. J Wrist Surg 08:112–117.

    23. Mulders MAM, Walenkamp MMJ, van Dieren S et al (2019) Volar plate fixation versus plaster immobilization in acceptably reduced extra-articular distal radial fractures: a multicenter randomized controlled trial. J Bone Joint Surg 101:787–796

    24. Selles CA, Mulders MAM, Winkelhagen J et al (2021) Volar plate fixation versus cast immobilization in acceptably reduced intra-articular distal radial fractures: a randomized controlled trial. J Bone Joint Surg 103:1963–1969.

    25. Ochen Y, Peek J, van der Velde D et al (2020) Operative vs nonoperative treatment of distal radius fractures in adults. JAMA Netw Open 3:e203497.

    26. Combined Randomised and Observational Study of Surgery for Fractures in the Distal Radius in the Elderly (CROSSFIRE) Study Group, Lawson A, Naylor J et al (2022) Plating vs closed reduction for fractures in the distal radius in older patients. JAMA Surg 157:563–571.

    27. Combined Randomised and Observational Study of Surgery for Fractures in the Distal Radius in the Elderly (CROSSFIRE) Study Group, Lawson A, Naylor JM et al (2021) Surgical plating vs closed reduction for fractures in the distal radius in older patients. JAMA Surg 156:229–237.

    28. Hassellund SS, Williksen JH, Laane MM et al (2021) Cast immobilization is non inferior to volar locking plates in relation to QuickDASH after one year in patients aged 65 years and older: a randomized controlled trial of displaced distal radius fractures. Bone Joint J 103-B:247–255.

    29. Johnson NJ, Carlbom DJ, Gaieski DF (2018) Ventilator management and respiratory care after cardiac arrest oxygenation, ventilation, infection, and injury. Chest 153:1466–1477.

    30. Thorninger R, Madsen ML, Waver D et al (2017) Complications of volar locking plating of distal radius fractures in 576 patients with 3.2 years follow-up. Injury 48:1104–1109.

  4. Reviews

    1. Shen O, Chen CT, Jupiter JB, Chen NC, Liu WC. Functional outcomes and complications after treatment of distal radius fracture in patients sixty years and over: A systematic review and network meta-analysis. Injury. 2023 Jul;54(7):110767. doi: 10.1016/j.injury.2023.04.054.

    2. Lari A, Nouri A, Alherz M, Prada C. Operative treatment of distal radius fractures involving the volar rim-A systematic review of outcomes and complications. Eur J Orthop Surg Traumatol. 2023 May 6.

    3. Khan S, Persitz J, Shrouder-Henry J, Khan M, Chan A, Paul R. Effect of Time-To-Surgery on Distal Radius Fracture Outcomes: A Systematic Review. J Hand Surg Am. 2023 May;48(5):435-443.

    4. Ying L, Cai G, Zhu Z, Yu G, Su Y, Luo H. Does pronator quadratus repair affect functional outcome following volar plate fixation of distal radius fractures? A systematic review and meta-analysis. Front Med (Lausanne). 2023 Feb 3;10:992493.

    5. Abdel Khalik H, Lameire DL, Kruse C, Hache PJ, Al-Asiri J. Management of Very Distal Ulna Fractures: A Systematic Review. J Orthop Trauma. 2023 Jul 1;37(7):e274-e281

    6. Raj V, Barik S, Richa. Comparison of above elbow and below elbow immobilisation for conservative treatment of distal end radius fracture in adults: A systematic review and meta-analysis of randomized clinical trials. Chin J Traumatol. 2023 Jul;26(4):204-210.

    7. Linnanmäki L, Hevonkorpi T, Repo J, Karjalainen T. Anterior locking plate versus non-operative treatment in different age groups with distal radial fractures: a systematic review and meta-analysis. J Hand Surg Eur Vol. 2023 Jun;48(6):532-543.

    8. Yang Q, Cai G, Liu J, Wang X, Zhu D. Efficacy of cast immobilization versus surgical treatment for distal radius fractures in adults: a systematic review and meta-analysis. Osteoporos Int. 2023 Apr;34(4):659-669.

    9. Norton B, Bugden B, Liu KP. Functional outcome measures for distal radius fractures: A systematic review. Hong Kong J Occup Ther. 2022 Dec;35(2):115-124.

    10. Oldrini LM, Feltri P, Albanese J, Lucchina S, Filardo G, Candrian C. Volar locking plate vs cast immobilization for distal radius fractures: a systematic review and meta-analysis. EFORT Open Rev. 2022 Sep 19;7(9):644-652.

    11. Jamnik AA, Pirkle S, Chacon J, Xiao AX, Wagner ER, Gottschalk MB. The Effect of Immobilization Position on Functional Outcomes and Complications Associated With the Conservative Treatment of Distal Radius Fractures: A Systematic Review. J Hand Surg Glob Online. 2021 Nov 8;4(1):25-31.

    12. Kunes JA, Hong DY, Hellwinkel JE, Tedesco LJ, Strauch RJ. Extensor Tendon Injury After Volar Locking Plating for Distal Radius Fractures: A Systematic Review. Hand (N Y). 2022 Dec;17(1_suppl):87S-94S.

    13. Shihab Z, Sivakumar B, Graham D, Del Piñal F. Outcomes of Arthroscopic-Assisted Distal Radius Fracture Volar Plating: A Meta-Analysis. J Hand Surg Am. 2022 Apr;47(4):330-340.e1

    14. Lee JK, Yoon BH, Kim B, Ha C, Kil M, Shon JI, Lee HI. Is early mobilization after volar locking plate fixation in distal radius fractures really beneficial? A meta-analysis of prospective randomized studies. J Hand Ther. 2023 Jan-Mar;36(1):196-207.

    15. Deng Z, Wu J, Tang K, Shu H, Wang T, Li F, Nie M. In adults, early mobilization may be beneficial for distal radius fractures treated with open reduction and internal fixation: a systematic review and meta-analysis. J Orthop Surg Res. 2021 Nov 24;16(1):691

    16. Chen Z, Zhu Y, Zhang W, Eltagy H, Elerian S. Comparison of Intramedullary Nail and Volar Locking Plate for Distal Radius Fractures: A Systematic Review and Meta-Analysis of Randomised Controlled Trials. Cureus. 2021 Sep 14;13(9):e17972.

    17. Fitzpatrick E, Sharma V, Rojoa D, Raheman F, Singh H. The use of cone-beam computed tomography (CBCT) in radiocarpal fractures: a diagnostic test accuracy meta-analysis. Skeletal Radiol. 2022 May;51(5):923-934.

  5. Guidelines

    German guideline, as of 2021:

    S2e Guideline Distal Radius Fracture      

    The American Academy of Orthopaedic Surgeons Board & The American Society for Surgery of the Hand, as of 2020:

    Management of Distal Radius Fractures

    British Orthopaedic Association and British Society for Surgery of the Hand, as of 2018:

    Best practice for management of Distal Radial Fractures (DRFs)

  6. literature search

    Literature search on the pages of pubmed.