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Perioperative management - Endovascular Therapy of a Penetrating Atheromatous Aortic Ulcer of the Descending Aorta (PAU, TEVAR)

  1. Indications

    Indications

    In the article, the endoluminal exclusion of a penetrating atheromatous ulcer (PAU, eccentric 32 x 24 mm) of the descending aorta is demonstrated. Due to two previous vascular surgical operations in the left groin and severe arteriosclerosis, an extraperitoneal exposure of the external iliac artery is performed.

    For a diameter or depth of the ulcer of ≥ 20 mm, elective endovascular treatment is indicated. In cases of signs of impending rupture (pain, extra-aortic blood), endovascular treatment is urgent. Pain is mentioned as one of the main criteria for urgent surgical intervention.

  2. Contraindications

    • none except ASA IV
  3. Preoperative Diagnostics

    Thorough vascular surgical examination:

    • Pulse status
    • Doppler legs
    • if necessary, walking distance test with concurrent PAD  and poorly palpable foot pulses
    • Abdominal ultrasound
    • Color duplex carotids
    • Echocardiogram
    • Stress ECG
    • Laboratory investigations (electrolytes, coagulation, renal values, blood count, blood lipids, blood group)
    • Chest X-ray
    • Spiral CT thorax-abdomen
  4. Special Preparation

    • Determine blood type, if necessary provide blood products
    • Depilate surgical area
    • if necessary insert bladder catheter
    • prophylactic antibiotic therapy is usually performed and is recommended by the German Society for Vascular Surgery (single-shot Cefuroxime 30 minutes before skin incision), however, the benefit is currently being discussed due to the resistance issues (RKI). 
  5. Informed Consent

    General Surgical Risks

    • Allergy/Intolerance e.g. to latex, medications; circulatory shock, intensive care measures; very rarely severe, possibly permanent damage (organ failure, brain damage, paralysis)
    • Wound Infections: medication or surgical measures; sepsis
    • Thromboembolisms of the leg and pelvic veins, pulmonary embolism; preventive heparinization → HIT II
    • Skin, Tissue, and Nerve Damage due to positioning and procedure-related measures
    • Keloids

    Specific Procedure Risks

    • Temporary Fever
    • Vascular Injuries due to advancement of catheters, stent prosthesis; surgical hemostasis, blood transfusions, immediate transition to open surgery; donor blood → hepatitis, HIV
    • Post-Bleeding, Hematomas; possibly surgical measures
    • Injury to Skin Nerves; sensory disturbances, possibly permanent
    • Leg Edema due to damage to lymphatic vessels in the groin; compression stockings, in case of chronic lymphedema medication or physical measures (lymphatic drainage)
    • Aneurysm at puncture sites of the arteries or vascular fistula to the adjacent vein; seroma formation
    • Infections of the Stent Prosthesis: within days, months, also after years → endocarditis, sepsis; surgical removal of the infected prosthesis
    • Injury to Adjacent Organs due to fixation of the aortic prosthesis (esophagus, intestine, lung) → surgical measures, possibly removal of the prosthesis
    • Misplacement of the Aortic Prosthesis → possibly open surgical correction
    • Leakage of the Aortic Prosthesis → correction by clipping, extension of the existing prosthesis, possibly also open correction
    • Side Effects from Iodine-Containing X-Ray Contrast Media → temporary kidney function impairments, rarely permanent damage (dialysis), possibly hyperthyroidism
    • Potency Disorders in Men: rarely erectile dysfunction, possibly permanent

    Risks from Insufficient Blood Flow

    • Extremities: due to occlusion of the stent prostheses and adjacent vascular segments by thrombi, perfusion disturbances of the limbs; renewed surgical intervention, possibly amputation
    • Kidneys: restrictions in kidney function due to thromboembolisms → surgical correction, temporary or also permanent dialysis
    • Intestine: due to thromboembolisms or misplacement of the vascular prosthesis; surgical measures, intestinal resection, possibly (permanent) artificial anus
    • Spinal Cord: temporary sensory disturbances and paralysis of the legs, possibly permanent paraplegia
    • Stroke: due to thromboembolisms → paralysis, hearing, speech or vision disturbances, possibly loss of speech, deafness, blindness
    • Liver: functional impairment with "jaundice", especially in pre-existing liver disease
Anesthesia

ITN ... - Operations in general, visceral and transplant surgery, vascular surgery and thoracic sur

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