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Complications - complete hysterectomy, bilateral adnexectomy, sentinel node biopsy pelvic bilateral laparoscopic, robot-assisted laparoscopy (DaVinci)

  1. Intraoperative Complications

    Bleeding:

    • Blood loss > 1000 ml in 1–3% of cases
    • Injury to the iliac artery or uterine arteries
    • Pelvic hematomas due to inadequate hemostasis
    • Injury to the iliac vein or iliac artery, need for vascular reconstruction very rare

    Lymphatic vessel injuries:

    • Lymphorrhea common, usually self-limiting, lymphatic fistula formation very rare

    Injuries to adjacent organs:

    • Bladder injury (0.59–1.0%), increased with previous surgeries (e.g., cesarean section)
    • Ureteral injury (0.09–0.3%), often recognized postoperatively
    • Bowel injury (0.2–0.4%), more common with adhesions or endometriosis

    CO₂ insufflation complications:

    • Subcutaneous emphysema or gas embolism
    • Pneumothorax or mediastinal emphysema with excessive insufflation pressure

    Nerve injuries:

    • Lesion of the obturator nerve or sacral plexus
    • Postoperative neuropathic pain

    Technical complications:

    • Conversion to laparotomy (2–4%), e.g., in cases of massive adhesions
    • Inadequate coagulation or hemostasis
  2. Early postoperative complications:

    Bleeding & Hematomas:

    • Postoperative bleeding (0.94–1.8%)
    • Pelvic hematoma or abdominal hematoma

    Urinary tract complications:

    • Urinary retention (0.5–1.6%) due to bladder neck edema
    • Urinary tract infections (0.7–2.2%) due to catheterization
    • Fistula formation with unrecognized bladder or ureter injury

    Bowel dysfunction:

    • Postoperative ileus (0.09–1.0%), especially with adhesions
    • Constipation due to altered pelvic floor statics

    Infections:

    • Wound infection (0.9–2.4%) at trocar sites
    • Pelvic infection, hematoma, or abscess (1.0–5.4%)
    • Sepsis (0.03%)

    Thromboembolic events:

    • Deep vein thrombosis or pulmonary embolism (0.02–0.03%)

    Vaginal complications:

    • Dyspareunia due to scar formation
    • Vaginal cuff dehiscence (0.64–1.64%), risk increased with laparoscopic technique

    Lymphocele

    • Fluid accumulation in the pelvic wall after sentinel node biopsy, usually self-limiting, drainage may be necessary, significantly less common than with systematic pelvic and para-aortic lymphadenectomy (here 20%)
  3. Long-term effects

    Pelvic Floor Weakness & Prolapse:

    • Increased risk for vaginal vault prolapse
    • Possible need for a follow-up surgery

    Urinary Incontinence & Bladder Dysfunction:

    • Stress or urge incontinence
    • Altered bladder position with postoperative dysfunction

    Bowel Dysfunction:

    • Chronic constipation due to altered anatomy
    • Risk for rectocele or enterocele

    Sexual Dysfunction:

    • Dyspareunia due to vaginal shortening or scar traction
    • Decreased lubrication after oophorectomy

    Chronic Pain:

    • Neuropathic complaints due to nerve irritation
    • Scar pain in the pelvis

    Psychological Consequences:

    • Postoperative depression or anxiety disorders
    • Feeling of "loss of femininity"

    Lymphedema: very rare

    Persistent Lymphocele: very rare

  4. Reference

    1. Brummer TH, Jalkanen J, Fraser J, Heikkinen AM, Kauko M, Makinen J, et al. FINHYST, a prospective study of 5279 hysterectomies: complications and their risk factors. Hum Reprod. 2011;26(7):1741-51. 
    2. Chapron C, Querleu D, Bruhat MA, Madelenat P, Fernandez H, Pierre F, et al. Surgical complications of diagnostic and operative gynecological laparoscopy: a series of 29,966 cases. Hum Reprod. 1998;13(4):867-72. 
    3. McPherson K, Metcalfe MA, Herbert A, Maresh M, Casbard A, Hargreaves J, et al. Severe complications of hysterectomy: the VALUE study. BJOG: an international journal of obstetrics and gynecology. 2004;111(7):688-94
    4. AQUA Institute for Healthcare GmbH Mh-, 37073 Göttingen. AQUA. Federal evaluation for the procedure year 2012. 15/1 Gynecological Operations. https://wwwsqgde/downloads/Bundesauswertungen/2012/bu_Gesamt_15N1-GYNOP_2012pdf. 2013;Last accessed: 05.01.2015. 
    5. Zikan M, Fischerova D, Pinkavova I, Slama J, Weinberger V, Dusek L, Cibula D. A prospective study examining the incidence of asymptomatic and symptomatic lymphoceles following lymphadenectomy in patients with gynecological cancer. Gynecol Oncol. 2015 May;137(2):291-8. doi: 10.1016/j.ygyno.2015.02.016. Epub 2015 Feb 24. PMID: 25720294.