The occurrence of an accidental uterine sarcoma during a hysterectomy or myoma surgery ranges between 1/205 and 1/7400 (0.49%-0.014%). In a meta-analysis of 10,120 patients, a frequency of 0.29% was found. Due to this risk, electromechanical morcellators were withdrawn, by Ethicon in 2014 and Karl Storz in 2021.
In imaging, there is no reliable preoperative distinction between benign and malignant findings. However, with clinical examinations, "soft markers" in transvaginal ultrasound, possibly MRI, and a detailed medical history, the risk can probably be reduced. Benign uterine fibroids do not contraindicate morcellation. It is therefore important to preoperatively inform about the potential dangers of morcellation, alternative approaches and their respective perioperative risks (morbidity and mortality of other surgical techniques), and on the other hand, the low incidence of sarcomas.
The use of retrieval bags also cannot exclude the dissemination of tumor cells. There are different techniques of morcellation:
Manual in bag Morcellation: Insertion of the retrieval bag, luxation of the uterus into it, minilaparotomy, and fragmentation using a scalpel (extra-abdominal).
Contained power Morcellation: Insertion of a retrieval bag, luxation of the uterus into it, electromechanical morcellation within the bag (intra-abdominal).
Morcellation should not be performed in postmenopausal patients with newly developed fibroids or fibroids with a tendency to grow or newly symptomatic fibroids.