Evidence - Appendectomy, open

Compared with medical treatment (antibiotics, local cooling, etc.) in patients with clinical diagnosis of acute appendicitis, surgery results in:

• • Lower rate of recurrent appendicitis
  • Similar length of hospital stay and work disability
  • Higher pain intensity during the first few days 

Compared with medical treatment in patients with chronic right lower quadrant pain, surgery results in:

• • Less pain in the long run
  • Slightly higher rates of adverse events

Regarding incidental appendectomy in asymptomatic patients, there are:

• • No results from high-quality trials.

In open appendectomy simple ligation of the appendiceal stump versus stump inversion (= purse string suture) resulted in:

• • Comparable or even lower rates of local complications 
  • Shorter operating times

Patients with suspected appendicitis may already be administered analgesics upon hospitalization because:

• • This reduces pain effectively
  • Without affecting the physical examination of the abdomen

The Identification of the Optimal Treatment Strategy for Complex Appendicitis in the Pediatric Population

Operative Versus Non-Operative Management for Appendicitis With Abscess or Phlegmon

A Multicentre, Randomized Controlled Trial Comparing Appendectomy Versus Non-Operative Treatment For Acute Non-Perforated Appendicitis in Children

A Randomized, Controlled Multicenter Feasibility Pilot Trial on Imaging Confirmed Uncomplicated Acute Appendicitis: Appendectomy vs. Symptomatic Treatment in Pediatric Patients (the APPSYPP) Trial Study Protocol

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