Evidence - Diathermy excision / contact destruction of anal condylomata acuminata

The surgical treatment of condyloma by excision or local destruction (excision/destruction with scissors, diathermy, laser, or cryotherapy; scalpel excision) seems to deliver the best results with healing rates of up to 94% and a recurrence rate of 29% after three months. Diathermy tends to result in better data than cryotherapy. It should be noted that these are epidermal tumors. The destruction of deep skin layers does not offer any benefit in terms of radicality and prevention of recurrence. However, it risks functionally adverse scarring.

Carbon Dioxide Laser Ablation Versus Electrocoagulation - a Prospective, Randomized Multicenter Trial Comparing Two Surgical Treatments in Women Undergoing Therapy for Condyloma Acuminata

Adjuvant Imiquimod Therapy to Reduce Recurrence Rate in Patients After Surgical Therapy of Anal HPV (Human Papilloma Virus)-Lesions

Stone KM, Becker TM, Hadgu A et al.: Treatment of external genital warts: a randomised clinical trial
comparing podophyllin, cryotherapy, and electrodesiccation. Genitourin Med. 66, 16-19, 1990

Moore RA, Edwards JE, Hopwood J et al.: Imiquimod for the treatment of genital warts: a quantitative
systematic review. BMC Infect Dis 2001

Jensen SL: Comparison of podophyllin application with simple surgical excision in clearance and recurrence
of perianal condylomata acuminata. Lancet 2, 1146-1148, 1985

Khawaja HT: Podophyllin versus scissor excision in the treatment of perianal condylomata acuminata: a
prospective study. Br J Surg 76, 1067-1068, 1989